Synthesis and Charactrization of some Hetrocyclic Compounds from Ninhydrin and Study of its Effect on Amylase Enzyme in Serum

  • Ibtihal Abdalla

Abstract

Ninhydrin is a chemical compound that is commonly used in analytical chemistry. In this research, ninhydrin was utilized to prepare some heterocyclic derivatives. It was reacted with hydrazine to make compound (1), which was the starting material to synthesize other heterocyclic derivatives in this research. These compounds were characterized by (FT-IR) and (H-NMR) techniques. The biological effect of the prepared compounds were tested against the activity of amylase enzyme in serum. These compounds resulted in deactivating the amylase enzyme in a percentage rate of (11.43, 36.49) %, which proves their effectiveness against the enzyme.

Published
Jun 11, 2018
How to Cite
ABDALLA, Ibtihal. Synthesis and Charactrization of some Hetrocyclic Compounds from Ninhydrin and Study of its Effect on Amylase Enzyme in Serum. Tikrit Journal for Dental Sciences, [S.l.], v. 6, n. 1, p. 44-51, june 2018. ISSN 2073-1213. Available at: <https://tjds.tu.edu.iq/index.php/j/article/view/67>. Date accessed: 30 sep. 2022.